A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability.

The human genome encodes thousands of long noncoding RNA (lncRNA) genes; the function of majority of them is poorly understood. Aberrant expression of a significant number of lncRNAs is observed in various diseases, including cancer. To gain insights into the role of lncRNAs in breast cancer progres...

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Bibliographic Details
Main Authors: Mahdieh Jadaliha, Omid Gholamalamdari, Wei Tang, Yang Zhang, Ana Petracovici, Qinyu Hao, Aamira Tariq, Tae Gyoon Kim, Sarah E Holton, Deepak K Singh, Xiao Ling Li, Susan M Freier, Stefan Ambs, Rohit Bhargava, Ashish Lal, Supriya G Prasanth, Jian Ma, Kannanganattu V Prasanth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007802