Powder Self-Emulsifying Drug Delivery System for Mitotane: In Vitro and In Vivo Evaluation

Powder Self-Emulsifying Drug Delivery System for Mitotane: In Vitro and In Vivo Evaluation

Drug Delivery Systems (DDSs) of known drugs are prominent candidates for new and more effective treatments of various diseases, as they may increase drug solubility, dissolution velocity, and bioavailability. Mitotane (o,p′-dichlorodimethyl dichloroethane [o,p′-DDD]) is used for the treatment of adr...

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Bibliographic Details
Main Authors: Mohamed Skiba, Valentin Lefébure, Frederic Bounoure, Nicolas Milon, Michael Thomas, Herve Lefebvre, Lahiani-Skiba Malika
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pharmaceutics
Subjects:
mitotane
Lysodren<sup>®</sup>
α-cyclodextrin
adrenocortical carcinoma
Cushing’s disease
bioavailability
Online Access:https://www.mdpi.com/1999-4923/16/9/1194

Internet

https://www.mdpi.com/1999-4923/16/9/1194

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