Timing the emergence of resistance to anti-HIV drugs with large genetic barriers.

New antiretroviral drugs that offer large genetic barriers to resistance, such as the recently approved inhibitors of HIV-1 protease, tipranavir and darunavir, present promising weapons to avert the failure of current therapies for HIV infection. Optimal treatment strategies with the new drugs, howe...

Full description

Bibliographic Details
Main Authors: Pankhuri Arora, Narendra M Dixit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2643484?pdf=render