The N-Terminal Region of Plasmodium falciparum MSP10 Is a Target of Protective Antibodies in Malaria and Is Important for PfGAMA/PfMSP10 Interaction

The N-Terminal Region of Plasmodium falciparum MSP10 Is a Target of Protective Antibodies in Malaria and Is Important for PfGAMA/PfMSP10 Interaction

Clinical manifestation of malaria is mainly due to intra-erythrocytic development of Plasmodium parasites. Plasmodium falciparum merozoites, the invasive form of the blood-stage parasite, invade human erythrocytes in a complex but rapid process. This multi-step progression involves interactions betw...

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Bibliographic Details
Main Authors: Hikaru Nagaoka, Bernard N. Kanoi, Kana Jinoka, Masayuki Morita, Thangavelu U. Arumugam, Nirianne M. Q. Palacpac, Thomas G. Egwang, Toshihiro Horii, Takafumi Tsuboi, Eizo Takashima
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
malaria
Plasmodium falciparum
blood-stage vaccine
PfMSP10
PfGAMA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02669/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02669/full

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