Phenotypic Detection of Hemin-Inducible Trimethoprim-Sulfamethoxazole Heteroresistance in Staphylococcus aureus

Phenotypic Detection of Hemin-Inducible Trimethoprim-Sulfamethoxazole Heteroresistance in Staphylococcus aureus

ABSTRACT Trimethoprim-sulfamethoxazole (SXT) is a valuable second-line antimicrobial agent to treat methicillin-resistant Staphylococcus aureus infections. Discrepancies between various antibiotic susceptibility testing (AST) methods for SXT susceptibility in S. aureus have been described. Here, we...

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Bibliographic Details
Main Authors: Dennis Nurjadi, Quan Chanthalangsy, Elfi Zizmann, Vanessa Stuermer, Maximilian Moll, Sabrina Klein, Sébastien Boutin, Klaus Heeg, Philipp Zanger
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:Microbiology Spectrum
Subjects:
MRSA
Staphylococcus aureus
antibiotic susceptibility testing
co-trimoxazole
hemin
heteroresistance
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.01510-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.01510-21

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