Identification of a Glypican-3 Binding Peptide From a Phage-Displayed Peptide Library for PET Imaging of Hepatocellular Carcinoma

Identification of a Glypican-3 Binding Peptide From a Phage-Displayed Peptide Library for PET Imaging of Hepatocellular Carcinoma

Tumor-targeting peptides functioned as molecular probes are essential for multi-modality imaging and molecular-targeting therapy in caner theronostics. Here, we performed a phage-displayed bio-panning to identify a specific binding peptide targeting Glypican-3 (GPC-3), a promising biomarker in hepat...

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Bibliographic Details
Main Authors: Jiayao Yan, Xiaoxiao Yu, Xiaotong Chen, Fangcen Liu, Fangjun Chen, Naiqing Ding, Lixia Yu, Fanyan Meng, Jie Shen, Jia Wei, Baorui Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
phage display
tumor-targeting peptide
glypican-3
hepatocellular carcinoma
PET imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.679336/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.679336/full

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