Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia

Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia

Abstract Background The constitutive hyper-activation of phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathways has frequently been associated with acute myeloid leukemia (AML). While many inhibitors targeting these pathways have been deve...

全面介绍

书目详细资料
Main Authors: Yanan Gao, Juan Gao, Minghao Li, Yawei Zheng, Yajie Wang, Hongyan Zhang, Weili Wang, Yajing Chu, Xiaomin Wang, Mingjiang Xu, Tao Cheng, Zhenyu Ju, Weiping Yuan
格式: 文件
语言:English
出版: BMC 2016-04-01
丛编:Journal of Hematology & Oncology
主题:
Rheb1
mTORC1
MLL-AF9
Leukemia
Rapamycin
3BDO
在线阅读:http://link.springer.com/article/10.1186/s13045-016-0264-3

因特网

http://link.springer.com/article/10.1186/s13045-016-0264-3

相似书籍