The role of PKC/PKR in aging, Alzheimer's disease, and perioperative neurocognitive disorders

The role of PKC/PKR in aging, Alzheimer's disease, and perioperative neurocognitive disorders

BackgroundThe incidence of perioperative neurocognitive disorders (PNDs) is reportedly higher in older patients. Mitochondrial and synaptic dysfunctions have consistently been demonstrated in models of aging and neurodegenerative diseases; nonetheless, their role in PND is not well understood.Method...

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Bibliographic Details
Main Authors: Wenping Lu, Sailan Tang, Ao Li, Qiuyue Huang, Mengyun Dou, Ye Zhang, Xianwen Hu, Raymond Chuen Chung Chang, Gordon Tin Chun Wong, Chunxia Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
perioperative neurocognitive disorders
autophagy
protein kinase C
double-stranded RNA (dsRNA)-dependent protein kinase
laparotomy
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.973068/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.973068/full

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