3158 Sunitinib-Induced Cardiotoxicity in an Engineered Cardiac Microtissue Model

OBJECTIVES/SPECIFIC AIMS: The aims of this study are threefold. Firstly, we are examining the effects of increased in vitro afterload (a proxy for hypertension) on human induced pluripotent stem cell cardiomyocyte (hiPSC-CM) response to sunitinib in a durable and dynamic cardiac microtissue culture...

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Bibliographic Details
Main Authors: Carissa Livingston, Abhinay Ramachandran, Elise Corbin, Alexia Vite, Alexander Bennett, Kenneth Margulies
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866119002620/type/journal_article