Hepatic PKA inhibition accelerates the lipid accumulation in liver

Hepatic PKA inhibition accelerates the lipid accumulation in liver

Abstract Background/aims Liver lipid accumulation induced by high-fat diet (HFD) is an early onset process of non-alcoholic fatty liver diseases (NAFLD). Protein kinase A (PKA) is known to be involved in hepatic lipid metabolism. However, the role of PKA in NAFLD has not been well tested in vivo due...

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Bibliographic Details
Main Authors: Jining Yang, Xiaoying Zhang, Long Yi, Ling Yang, Wei Eric Wang, Chunyu Zeng, Mantian Mi, Xiongwen Chen
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Nutrition & Metabolism
Subjects:
Protein kinase a
Non-alcoholic fatty liver diseases
Lipid metabolism
RNA sequencing
Online Access:http://link.springer.com/article/10.1186/s12986-019-0400-5

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http://link.springer.com/article/10.1186/s12986-019-0400-5

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