IL-21 (rs2055979 and rs2221903)/<i>IL-21R</i> (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients

IL-21 (rs2055979 and rs2221903)/<i>IL-21R</i> (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients

Rheumatoid Arthritis (RA) is characterized by joint destruction, chronic inflammation, and autoantibody production. IL-21/IL-21R plays an essential role in the immunopathology of RA. Elevated IL-21 serum levels have been associated with RA and disease activity. Here, we evaluated the association of...

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Bibliographic Details
Main Authors: Noemi Magdalena Carreño-Saavedra, Itzel Viridiana Reyes-Pérez, Andrea Carolina Machado-Sulbaran, Gloria Esther Martínez-Bonilla, María Guadalupe Ramírez-Dueñas, José Francisco Muñoz-Valle, Valeria Olaya-Valdiviezo, Trinidad García-Iglesias, Erika Aurora Martínez-García, Pedro Ernesto Sánchez-Hernández
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
rheumatoid arthritis
SNP
polymorphism
IL-21
IL-21R
biomarkers
Online Access:https://www.mdpi.com/2073-4425/14/4/878

Internet

https://www.mdpi.com/2073-4425/14/4/878

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