PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts

PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts

IntroductionAlzheimer’s disease (AD) is indicated by a decrease in amyloid beta 42 (Aβ42) level or the Aβ42/Aβ40 ratio, and by increased levels of Tau with phosphorylated threonine at position 181 (pTau181) in cerebrospinal fluid (CSF) years before the onset of clinical symptoms. However, once only...

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Bibliographic Details
Main Authors: Anna-Lena Haas, Pauline Olm, Janine Utz, Eva-Maria Siegmann, Philipp Spitzer, Anna Florvaag, Manuel Alexander Schmidt, Arnd Doerfler, Piotr Lewczuk, Johannes Kornhuber, Juan Manuel Maler, Timo Jan Oberstein, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
magnetic resonance imaging
medial temporal lobe
tau proteins/cerebrospinal fluid*
amyloid beta-peptides/cerebrospinal fluid*
SNAP
ATN classification
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1121500/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1121500/full

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