A Qualitative Signature to Identify TERT Promoter Mutant High-Risk Tumors in Low-Grade Gliomas

A Qualitative Signature to Identify TERT Promoter Mutant High-Risk Tumors in Low-Grade Gliomas

Background: Telomerase reverse transcriptase promoter (TERT-p) mutation has been frequently found, but associated with contrary prognosis, in both low-grade gliomas and glioblastomas. For the low-grade gliomas (Grades II-III), TERT-p mutant patients have a better prognosis than the wildtype patients...

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Bibliographic Details
Main Authors: Weicheng Zheng, Ruolan Zhang, Ziru Huang, Jianpeng Li, Haonan Wu, Yuwei Zhou, Jinwei Zhu, Xianlong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
glioma
TERT promoter
biomarker
transcriptome
relative expression orderings
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.806727/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.806727/full

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