RAD21 is the core subunit of the cohesin complex involved in directing genome organization
Abstract Background The ring-shaped cohesin complex is an important factor for the formation of chromatin loops and topologically associating domains (TADs) by loop extrusion. However, the regulation of association between cohesin and chromatin is poorly understood. In this study, we use super-resol...
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-06-01
|
Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-023-02982-1 |