RAD21 is the core subunit of the cohesin complex involved in directing genome organization

RAD21 is the core subunit of the cohesin complex involved in directing genome organization

Abstract Background The ring-shaped cohesin complex is an important factor for the formation of chromatin loops and topologically associating domains (TADs) by loop extrusion. However, the regulation of association between cohesin and chromatin is poorly understood. In this study, we use super-resol...

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Main Authors: Yuao Sun, Xin Xu, Wenxue Zhao, Yu Zhang, Keyang Chen, Yongzheng Li, Xiaotian Wang, Mengling Zhang, Boxin Xue, Wanting Yu, Yingping Hou, Chaobin Wang, Wei Xie, Cheng Li, Daochun Kong, Shu Wang, Yujie Sun
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-02982-1

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