Reconstruction and Analysis of a Genome-Scale Metabolic Model of Ganoderma lucidum for Improved Extracellular Polysaccharide Production

Reconstruction and Analysis of a Genome-Scale Metabolic Model of Ganoderma lucidum for Improved Extracellular Polysaccharide Production

In this study, we reconstructed for the first time a genome-scale metabolic model (GSMM) of Ganoderma lucidum strain CGMCC5.26, termed model iZBM1060, containing 1060 genes, 1202 metabolites, and 1404 reactions. Important findings based on model iZBM1060 and its predictions are as follows: (i) The e...

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Bibliographic Details
Main Authors: Zhongbao Ma, Chao Ye, Weiwei Deng, Mengmeng Xu, Qiong Wang, Gaoqiang Liu, Feng Wang, Liming Liu, Zhenghong Xu, Guiyang Shi, Zhongyang Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
Ganoderma lucidum
extracellular polysaccharide
genome-scale metabolic model
biosynthetic pathway
phenylalanine
simulation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03076/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.03076/full

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