1,4-Disubstituted 1H-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties

1,4-Disubstituted 1H-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties

Peptidotriazolamers are hybrid foldamers with features of peptides and triazolamers, containing alternation of amide bonds and 1,4-disubstituted 1H-1,2,3-triazoles with conservation of the amino acid side chains. We report on the synthesis of a new class of peptidomimetics, containing 1,4-disubstitu...

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Bibliographic Details
Main Authors: David C. Schröder, Oliver Kracker, Tanja Fröhr, Jerzy Góra, Michał Jewginski, Anke Nieß, Iris Antes, Rafał Latajka, Antoine Marion, Norbert Sewald
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Chemistry
Subjects:
peptidotriazolamers
1
4-disubstituted 1H-1
2
3-triazole
peptide bond isoster
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00155/full

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https://www.frontiersin.org/article/10.3389/fchem.2019.00155/full

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