Molecular Characterization of Secreted Factors and Extracellular Vesicles-Embedded miRNAs from Bone Marrow-Derived Mesenchymal Stromal Cells in Presence of Synovial Fluid from Osteoarthritis Patients

Bone marrow-derived mesenchymal stromal cells (BMSCs)-based therapies show a great potential to manage inflammation and tissue degeneration in osteoarthritis (OA) patients. Clinical trials showed the ability to manage pain and activation of immune cells and allowed restoration of damaged cartilage....

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Bibliographic Details
Main Authors: Enrico Ragni, Carlotta Perucca Orfei, Federico Valli, Luigi Zagra, Laura de Girolamo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/11/1632