Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson’s Disease?

Subnormal GM1 in PBMCs: Promise for Early Diagnosis of Parkinson’s Disease?

The fact that Parkinson’s disease (PD) pathologies are well advanced in most PD patients by the time of clinical elucidation attests to the importance of early diagnosis. Our attempt to achieve this has capitalized on our previous finding that GM1 ganglioside is expressed at subnormal levels in virt...

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Bibliographic Details
Main Authors: Samar K. Alselehdar, Monami Chakraborty, Suman Chowdhury, Roy N. Alcalay, Matthew Surface, Robert Ledeen
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
early diagnosis
sporadic Parkinson’s disease
GBA variant of Parkinson’s
GM1 ganglioside
GD1a ganglioside
PBMCs
Online Access:https://www.mdpi.com/1422-0067/22/21/11522

Internet

https://www.mdpi.com/1422-0067/22/21/11522

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