(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 4-amino-3-phenylbutanoate hydrochloride: Synthesis and anticonvulsant activity

Ester based on l-menthol and phenibut ‒ (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 4-amino-3-phenylbutanoate hydrochloride was obtained in 78% yield using N,N′-dicyclohexylcarbodiimide as a coupling reagent along with catalytic amount of 4-dimethylaminopyridine. The obtained product was character...

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Bibliographic Details
Main Authors: Nesterkina Mariia, Musatov Vladimir, Honcharova Olena, Kravchenko Iryna
Format: Article
Language:English
Published: De Gruyter 2022-07-01
Series:Open Chemistry
Subjects:
Online Access:https://doi.org/10.1515/chem-2022-0189