Conflict between translation initiation and elongation in vertebrate mitochondrial genomes.
The strand-biased mutation spectrum in vertebrate mitochondrial genomes results in an AC-rich L-strand and a GT-rich H-strand. Because the L-strand is the sense strand of 12 protein-coding genes out of the 13, the third codon position is overall strongly AC-biased. The wobble site of the anticodon o...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1794132?pdf=render |