Engineering <i>Escherichia coli</i> for Efficient Aerobic Conversion of Glucose to Malic Acid through the Modified Oxidative TCA Cycle

Engineering <i>Escherichia coli</i> for Efficient Aerobic Conversion of Glucose to Malic Acid through the Modified Oxidative TCA Cycle

Malic acid is a versatile building-block chemical that can serve as a precursor of numerous valuable products, including food additives, pharmaceuticals, and biodegradable plastics. Despite the present petrochemical synthesis, malic acid, being an intermediate of the TCA cycle of a variety of living...

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Bibliographic Details
Main Authors: Alexandra Yu. Skorokhodova, Anastasiya A. Stasenko, Natalya V. Krasilnikova, Andrey Yu. Gulevich, Vladimir G. Debabov
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Fermentation
Subjects:
2-ketoglutarate decarboxylase
<i>Escherichia coli</i>
glucose
malic acid
succinate semialdehyde
Online Access:https://www.mdpi.com/2311-5637/8/12/738

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https://www.mdpi.com/2311-5637/8/12/738

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