Engineering PEG10-assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccination

Tumor neoantigen peptide vaccines hold potential for boosting cancer immunotherapy, yet efficiently co-delivering peptides and adjuvants to antigen-presenting cells in vivo remains challenging. Virus-like particle (VLP), which is a kind of multiprotein structure organized as virus, can deliver thera...

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Bibliographic Details
Main Authors: Ruijing Tang, Luobin Guo, Tingyu Wei, Tingting Chen, Huan Yang, Honghao Ye, Fangzhou Lin, Yongyi Zeng, Haijun Yu, Zhixiong Cai, Xiaolong Liu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/98579