Losartan Has a Comparable Effect to Human Recombinant ACE2 in Reducing Interleukin-6 (IL-6) Levels on Human Adipocytes Exposed to SARS-CoV-2 Spike Protein

BACKGROUND: High angiotensin-converting enzyme 2 (ACE2) expression in adipocyte cells facilitates the initiation of SARS-CoV-2 infection and triggers a cytokine storm. This finding suggests that obesity is an independent risk factor for the severity of the symptoms caused by COVID-19. The use of car...

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Bibliographic Details
Main Authors: Hanestya Oky Hermawan, Meity Ardiana, I Gde Rurus Suryawan, Primasitha Maharany Harsoyo, Muhammad Rafli
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2023-10-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/2552