Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer

Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer

Abstract Background It is important to identify biomarkers associated with BRCA mutation in women with early breast cancer (BC) to improve early identification of mutation carriers. Thus, in this study, we examined the protein expression of claudin (CLDN) 3, CLDN4, CLDN7, and E-cadherin. Moreover, w...

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Bibliographic Details
Main Authors: Sabine Danzinger, Yen Yen Tan, Margaretha Rudas, Marie-Theres Kastner, Sigrid Weingartshofer, Daniela Muhr, Christian F. Singer
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Cancer
Subjects:
Familial breast cancer
BRCA1
BRCA2
Tissue microarray
Immunohistochemistry
Claudin
Online Access:http://link.springer.com/article/10.1186/s12885-019-5908-6

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http://link.springer.com/article/10.1186/s12885-019-5908-6

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