Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women

Oral contraceptive pill (OCP) treatment alters the gene expression of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and plasminogen activator inhibitor-1 (PAI-1) in polycystic ovary syndrome (PCOS) women compared to drug-naive PCOS women

Abstract Background Polycystic ovary syndrome (PCOS) presents clinical symptoms of menstrual abnormalities, excessive hair growth (hirsutism), scalp hair loss, acne and infertility. Metabolic abnormalities such as obesity, insulin resistance, glucose intolerance and cardiovascular problems constitut...

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Main Authors: Syed Douhath Yousuf, Mohammad Ashraf Ganie, Uneeb Urwat, Syed Mudasir Andrabi, Mohammad Afzal Zargar, Mashooq Ahmad Dar, Mir Manzoor-ul-Rehman, Syed Mudassar, Fouzia Rashid
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Women's Health
Subjects:
Polycystic ovary syndrome
Oral contraceptive pill
Tumor necrosis factor-α
Plasminogen activator inhabitor-1
Monocyte chemoattractant protein-1
Inflammation
Online Access:https://doi.org/10.1186/s12905-023-02187-5

Internet

https://doi.org/10.1186/s12905-023-02187-5

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