Identification of histone H3 clipping activity in human embryonic stem cells

Posttranslational histone modifications are essential features in epigenetic regulatory networks. One of these modifications has remained largely understudied: regulated histone proteolysis. In analogy to the histone H3 clipping during early mouse embryonic stem cell differentiation, we report for t...

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Bibliographic Details
Main Authors: Liesbeth Vossaert, Paulien Meert, Ellen Scheerlinck, Pieter Glibert, Nadine Van Roy, Björn Heindryckx, Petra De Sutter, Maarten Dhaenens, Dieter Deforce
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000610