Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness

Diallyl Trisulfide Induces ROS-Mediated Mitotic Arrest and Apoptosis and Inhibits HNSCC Tumor Growth and Cancer Stemness

Despite advances in therapeutic approaches, the five-year survival rate for head and neck squamous cell carcinoma (HNSCC) patients is still less than fifty percent. Research has indicated that the consumption of Allium vegetables or processed garlic containing diallyl trisulfide (DATS) can lower the...

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Bibliographic Details
Main Authors: Sivapar V. Mathan, Ragini Singh, Su-Hyeong Kim, Shivendra V. Singh, Rana P. Singh
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
diallyl trisulfide
HNSCC
mitotic arrest
apoptosis
DNA damage
cancer stem cells
Online Access:https://www.mdpi.com/2072-6694/16/2/378

Internet

https://www.mdpi.com/2072-6694/16/2/378

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