Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II

Abstract Background We attempted to determine whether the inflammatory pathway HMGB1-TLR4 and the downstream pro-inflammatory cytokines is upregulated in focal cortical dysplasia (FCD) type II and whether there is a correlation between the TLR4 upregulation and disease duration or frequency of epile...

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Bibliographic Details
Main Authors: Zhongbin Zhang, Qingzhu Liu, Ming Liu, Hui Wang, Ying Dong, Taoyun Ji, Xiaoyan Liu, Yuwu Jiang, Lixin Cai, Ye Wu
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-018-1078-8