Hypnozoite depletion in successive Plasmodium vivax relapses.

Genotyping Plasmodium vivax relapses can provide insights into hypnozoite biology. We performed targeted amplicon sequencing of 127 relapses occurring in Indonesian soldiers returning to malaria-free Java after yearlong deployment in malarious Eastern Indonesia. Hepatic carriage of multiple hypnozoi...

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Bibliographic Details
Main Authors: Rintis Noviyanti, Kelly Carey-Ewend, Leily Trianty, Christian Parobek, Agatha Mia Puspitasari, Sujata Balasubramanian, Zackary Park, Nicholas Hathaway, Retno A S Utami, Saraswati Soebianto, Jeny Jeny, Frilasita Yudhaputri, Aditya Perkasa, Farah N Coutrier, Yusrifar K Tirta, Lenny Ekawati, Bagus Tjahyono, Inge Sutanto, Erni J Nelwan, Herawati Sudoyo, J Kevin Baird, Jessica T Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010648