Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria.

Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria.

Cerebral malaria (CM) is the most severe manifestation of Plasmodium falciparum infection in children and non-immune adults. Previous work has documented a persistent cognitive impairment in children who survive an episode of CM that is mimicked in animal models of the disease. Potential therapeutic...

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Main Authors: Patricia A Reis, Vanessa Estato, Tathiany I da Silva, Joana C d'Avila, Luciana D Siqueira, Edson F Assis, Patricia T Bozza, Fernando A Bozza, Eduardo V Tibiriça, Guy A Zimmerman, Hugo C Castro-Faria-Neto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003099&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003099&type=printable

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