Engineered human meniscus' matrix-forming phenotype is unaffected by low strain dynamic compression under hypoxic conditions.

Engineered human meniscus' matrix-forming phenotype is unaffected by low strain dynamic compression under hypoxic conditions.

Low oxygen and mechanical loading may play roles in regulating the fibrocartilaginous phenotype of the human inner meniscus, but their combination in engineered tissues remains unstudied. Here, we investigated how continuous low oxygen ("hypoxia") combined with dynamic compression would af...

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Bibliographic Details
Main Authors: Alexander R A Szojka, Colleen N Moore, Yan Liang, Stephen H J Andrews, Melanie Kunze, Aillette Mulet-Sierra, Nadr M Jomha, Adetola B Adesida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248292

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https://doi.org/10.1371/journal.pone.0248292

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