TELS: A Novel Computational Framework for Identifying Motif Signatures of Transcribed Enhancers

In mammalian cells, transcribed enhancers (TrEns) play important roles in the initiation of gene expression and maintenance of gene expression levels in a spatiotemporal manner. One of the most challenging questions is how the genomic characteristics of enhancers relate to enhancer activities. To da...

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Bibliographic Details
Main Authors: Dimitrios Kleftogiannis, Haitham Ashoor, Vladimir B. Bajic
Format: Article
Language:English
Published: Oxford University Press 2018-10-01
Series:Genomics, Proteomics & Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022918304340