SARM suppresses TRIF, TRAF3, and IRF3/7 mediated antiviral signaling in large yellow croaker Larimichthys crocea

As a TIR domain-containing molecular, sterile α-and armadillo motif-containing protein (SARM) acts as an adaptor in Toll-like receptor (TLR) signaling, and also plays important roles in mediating apoptosis and neuronal injury. In the present study, the ortholog of SARM, named as Lc-SARM, was cloned...

Full description

Bibliographic Details
Main Authors: Jia Xi Zhang, Ying Li, Jun Chun Tang, Kai Qing Li, Juan Juan Shen, Chang Liu, Yong Hua Jiang, Zi Ping Zhang, Yi Lei Wang, Peng Fei Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1021443/full