PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

PDE4B Proposed as a High Myopia Susceptibility Gene in Chinese Population

Myopia is the most common cause of refractive error worldwide. High myopia is a severe type of myopia, which usually accompanies pathological changes in the fundus. To identify high myopia susceptibility genes, DNA-pooling based genome-wide association analysis was used to search for a correlation b...

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Bibliographic Details
Main Authors: Fuxin Zhao, Wei Chen, Hui Zhou, Peter S. Reinach, Yuhan Wang, Suh-Hang H. Juo, Zhenglin Yang, Anquan Xue, Yi Shi, Chung-Ling Liang, Changqing Zeng, Jia Qu, Xiangtian Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Genetics
Subjects:
phosphodiesterase 4B (PDE4B)
genome-wide association (GWA)
high myopia (HM)
A549 cell lines
collagen
CRISPR/Cas9
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.775797/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.775797/full

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