Urinary Protein-Biomarkers Reliably Indicate Very Early Kidney Damage in Children With Alport Syndrome Independently of Albuminuria and Inflammation

Urinary Protein-Biomarkers Reliably Indicate Very Early Kidney Damage in Children With Alport Syndrome Independently of Albuminuria and Inflammation

Introduction: Alport syndrome (AS) is a hereditary type IV collagen disease. It starts shortly after birth, without clinical symptoms, and progresses to end-stage kidney disease early in life. The earlier therapy starts, the more effectively end-stage kidney disease can be delayed. Clearly then, to...

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Bibliographic Details
Main Authors: Heidrun Rhode, Alexandra Lüse, Bärbel Tautkus, Mary Nabity, Ulrike John-Kroegel, Friederike Weigel, Axel Dost, Julia Schitke, Oliver Metzing, Jan Böckhaus, Diana Rubel, Wieland Kiess, Oliver Gross
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Kidney International Reports
Subjects:
C4 binding protein
collagen type XIII
dogs
early screening
hyaluronan binding protein 2
proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024923015218

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http://www.sciencedirect.com/science/article/pii/S2468024923015218

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