Synthesis of long-wavelength-absorbing photosensitizer/nanoparticle conjugates and their in vitro PDT evaluation on colorectal cancer cell lines

Synthesis of long-wavelength-absorbing photosensitizer/nanoparticle conjugates and their in vitro PDT evaluation on colorectal cancer cell lines

Starting from purpurin-18, a stable purpurin-18 imide derivative with intensive absorption in the near infrared has been synthesized. The opening of the exocycle anhydride by a primary alkylamine bearing an adamantyl group, allows after cyclization the formation of an imide function. This reaction l...

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Bibliographic Details
Main Authors: Ndzimbou, Luce Janice, Chkair, Rayan, Ndong Ntoutoume, Gautier Mark Arthur, Diab-Assaf, Mona, Chemin, Guillaume, Liagre, Bertrand, Brégier, Frédérique, Sol, Vincent
Format: Article
Language:English
Published: Académie des sciences 2025-03-01
Series:Comptes Rendus. Chimie
Subjects:
Purpurinimide
Photosensitizers
Cellulose nanocrystals
Photodynamic therapy (PDT)
Colorectal cancer
Online Access:https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.383/

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https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.383/

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