Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis.

Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis.

The role the mammary epithelial circadian clock plays in gland development and lactation is unknown. We hypothesized that mammary epithelial clocks function to regulate mammogenesis and lactogenesis, and propose the core clock transcription factor BMAL1:CLOCK regulates genes that control mammary epi...

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Bibliographic Details
Main Authors: Theresa Casey, Aridany Suarez-Trujillo, Shelby Cummings, Katelyn Huff, Jennifer Crodian, Ketaki Bhide, Clare Aduwari, Kelsey Teeple, Avi Shamay, Sameer J Mabjeesh, Phillip San Miguel, Jyothi Thimmapuram, Karen Plaut
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248199

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https://doi.org/10.1371/journal.pone.0248199

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