Detection of trisomy 12 by fluorescent in situ hybridization (FISH) in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) presents a varying incidence of karyotypic abnormalities whose detection is complicated by difficulties in obtaining mitosis for analysis in this type of mature lymphocyte disorder. Since the introduction of molecular cytogenetics (FISH = fluorescent in situ hybrid...

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Main Authors: Maria de Lourdes L.F. Chauffaille, Eliana Azevedo Marques, Jose Salvador Rodrigues de Oliveira, Maria Madalena Rodrigues, Maria Stella Figueiredo, Maura Romeo, Mihoko Yamamoto, José Kerbauy
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2000-09-01
Series:Genetics and Molecular Biology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000300005