Innate immune dysregulation in multisystem inflammatory syndrome in children (MIS-C)

Abstract MIS-C is a systemic inflammation disorder with poorly characterised immunopathological mechanisms. We compared changes in the systemic immune response in children with MIS-C (n = 12, 5–13 years) to healthy controls (n = 14, 5–15 years). Analysis was done in whole blood treated with LPS. Exp...

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Bibliographic Details
Main Authors: Johana Isaza-Correa, Laura Ryan, Lynne Kelly, John Allen, Ashanty Melo, Jennifer Jones, Dean Huggard, Emer Ryan, Cilian Ó Maoldomhnaigh, Sarah Geoghehan, Patrick Gavin, Timothy Ronan Leahy, Karina Butler, Bridget Freyne, Eleanor J. Molloy
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43390-6