Synergistic Effects of Moderate Therapeutic Hypothermia and Levosimendan on Cardiac Function and Survival After Asphyxia‐Induced Cardiac Arrest in Rats

Synergistic Effects of Moderate Therapeutic Hypothermia and Levosimendan on Cardiac Function and Survival After Asphyxia‐Induced Cardiac Arrest in Rats

Background This study investigated whether levosimendan, an inotropic calcium sensitizer, when combined with moderate therapeutic hypothermia, may exert synergistic benefits on post–cardiac arrest myocardial dysfunction and improve outcomes. Methods and Results After 9.5‐minute asphyxia‐induced card...

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Bibliographic Details
Main Authors: Chih‐Hung Wang, Wei‐Tien Chang, Min‐Shan Tsai, Chien‐Hua Huang, Wen‐Jone Chen
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
brain injury
cardiac arrest
cardiac dysfunction
hypothermia
inflammation
levosimendan
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.016139

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.016139

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