Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR-mutant lung adenocarcinoma.

Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR-mutant lung adenocarcinoma.

Several ultra-sensitive methods for T790M in plasma cell-free DNA (cfDNA) have been developed for lung cancer. The correlation between mutation-allele frequency (MAF) cut-off, drug responsiveness, and outcome prediction is an unmet needs and not fully addressed. An innovative combination of peptide...

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Bibliographic Details
Main Authors: Kang-Yi Su, Jeng-Sen Tseng, Keng-Mao Liao, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Pan-Chyr Yang, Sung-Liang Yu, Gee-Chen Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6239293?pdf=render

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http://europepmc.org/articles/PMC6239293?pdf=render

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