Synthesis of Functionalized Thiophene Based Pyrazole Amides via Various Catalytic Approaches: Structural Features through Computational Applications and Nonlinear Optical Properties

Synthesis of Functionalized Thiophene Based Pyrazole Amides via Various Catalytic Approaches: Structural Features through Computational Applications and Nonlinear Optical Properties

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In the present study, pyrazole-thiophene-based amide derivatives were synthesized by different methodologies. Here, 5-Bromothiophene carboxylic acid (<b>2</b>) was reacted with substituted, unsubstituted, and protected pyrazole to synthesize the amide. It was observed that unsubstituted...

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Bibliographic Details
Main Authors: Iram Kanwal, Nasir Rasool, Syeda Huda Mehdi Zaidi, Zainul Amiruddin Zakaria, Muhammad Bilal, Muhammad Ali Hashmi, Adeel Mubarik, Gulraiz Ahmad, Syed Adnan Ali Shah
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
pyrazole
amides
arylation
palladium
cross-coupling
computational
Online Access:https://www.mdpi.com/1420-3049/27/2/360

Internet

https://www.mdpi.com/1420-3049/27/2/360

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