Microbial dysbiosis and childhood asthma development: Integrated role of the airway and gut microbiome, environmental exposures, and host metabolic and immune response

Asthma is a chronic and heterogeneous respiratory disease with many risk factors that typically originate during early childhood. A complex interplay between environmental factors and genetic predisposition is considered to shape the lung and gut microbiome in early life. The growing literature has...

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Bibliographic Details
Main Authors: Conglin Liu, Heidi Makrinioti, Sejal Saglani, Michael Bowman, Lih-Ling Lin, Carlos A. Camargo, Kohei Hasegawa, Zhaozhong Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1028209/full