Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways

Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways

Abstract Background Osteoarthritis (OA) is a common degenerative joint condition marked by inflammation and cartilage breakdown. Currently, there is a dearth of treatment medications that can clearly slow the course of OA. Glaucocalyxin A (GLA) is a diterpene chemical identified and extracted from R...

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Bibliographic Details
Main Authors: Xin Hong, Xuqiang Liu, Bo Li, Shoujie Shi, Kai Xiao, Tiantian Xu, Yaoyang Nie, Min Dai, Meisong Zhu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
OA
Glaucocalyxin A
NF-κB
MAPK
Extracellular matrix
Online Access:https://doi.org/10.1186/s13018-024-04640-z

Internet

https://doi.org/10.1186/s13018-024-04640-z

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