Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice

Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice

Abstract Background Osteoarthritis (OA) is a chronic degenerative joint disease characterized by loss of joint function, which seriously reduces the quality of life of the elderly and imposes a heavy socioeconomic burden worldwide. Monotropein (MON), the main active ingredient of Morinda officinalis...

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Bibliographic Details
Main Authors: Zhen Li, Zhenyue Chen, Jiayi Chen, Zhutong Liu, Zehui Li, He Sun, Xiaochao Wang, Jinqiang Wei, Xuewei Cao, Decai Zheng
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Chinese Medicine
Subjects:
Monotropein
Osteoarthritis
Cartilage matrix degradation
Apoptosis
Pyroptosis
Online Access:https://doi.org/10.1186/s13020-023-00748-2

Internet

https://doi.org/10.1186/s13020-023-00748-2

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