A systematic exploration reveals the potential of spermidine for hypopigmentation treatment through the stabilization of melanogenesis-associated proteins
Abstract Spermidine (SPD), a polyamine naturally present in living organisms, is known to prolong the lifespan of animals. In this study, the role of SPD in melanogenesis was investigated, showing potential as a pigmenting agent. SPD treatment increased melanin production in melanocytes in a dose de...
Main Authors: | Sofia Brito, Hyojin Heo, Byungsun Cha, Su-Hyun Lee, Sehyun Chae, Mi-Gi Lee, Byeong-Mun Kwak, Bum-Ho Bin |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-18629-3 |
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