Minocycline Inhibits Microglial Activation and Improves Visual Function in a Chronic Model of Age-Related Retinal Degeneration

Minocycline Inhibits Microglial Activation and Improves Visual Function in a Chronic Model of Age-Related Retinal Degeneration

Age-related macular degeneration (AMD) is a chronic disease, which progresses slowly from early to late stages over many years. Inflammation critically contributes to the pathogenesis of AMD. Here, we investigated the therapeutic potential of minocycline in a chronic model of AMD (i.e., the <i>...

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Bibliographic Details
Main Authors: Xuan Du, Eimear M. Byrne, Mei Chen, Heping Xu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
ageing
inflammation
neurodegeneration
immunomodulation
age-related macular degeneration
neuroprotection
Online Access:https://www.mdpi.com/2227-9059/10/12/3222

Internet

https://www.mdpi.com/2227-9059/10/12/3222

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