New insights into Trypanosoma cruzi genetic diversity, and its influence on parasite biology and clinical outcomes

New insights into Trypanosoma cruzi genetic diversity, and its influence on parasite biology and clinical outcomes

Chagas disease, caused by Trypanosoma cruzi, remains a serious public health problem worldwide. The parasite was subdivided into six distinct genetic groups, called “discrete typing units” (DTUs), from TcI to TcVI. Several studies have indicated that the heterogeneity of T. cruzi species directly af...

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Bibliographic Details
Main Authors: Marina Malheiros Araújo Silvestrini, Glaucia Diniz Alessio, Bruna Estefânia Diniz Frias, Policarpo Ademar Sales Júnior, Márcio Sobreira Silva Araújo, Carolina Malheiros Araújo Silvestrini, Gustavo Eustáquio Brito Alvim de Melo, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Helen Rodrigues Martins
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Chagas disease
Trypanosoma cruzi
DTU
infectivity
immune response
pathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1342431/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1342431/full

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