MALTA: A calculator for estimating the coverage with shRNA, CRISPR, and cDNA libraries

Genetic screens using shRNA, CRISPR, or cDNA libraries rely on adequately transferring the library into cells for further assay. These libraries can have many different elements and each element can be present at different copy numbers within a given pooled library. Calculating how many recipient ce...

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Bibliographic Details
Main Authors: Venkatramanan Krishnamani, Mark A. Stamnes, Robert C. Piper
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:SoftwareX
Online Access:http://www.sciencedirect.com/science/article/pii/S2352711018301304